300 models ranked for pharmaceutical and life sciences. Scored with bonuses for reasoning (research analysis), large context (papers/patents), JSON mode (structured data), web search (literature), and function calling.
| # | Model | Score |
|---|---|---|
| 1 | GPT-5.4 ProOpenAI | 94 |
| 2 | GPT-5.4OpenAI | 94 |
| 3 | GPT-5.4 MiniOpenAI | 93 |
| 4 | GPT-5.2 ProOpenAI | 93 |
| 5 | GPT-5.2OpenAI | 93 |
| 6 | Claude Opus 4.6Anthropic | 92 |
| 7 | GPT-5 ProOpenAI | 92 |
| 8 | o3 Deep ResearchOpenAI | 92 |
| 9 | Claude Opus 4.5Anthropic | 90 |
| 10 | GPT-5OpenAI | 90 |
| 11 | Claude Sonnet 4.6Anthropic | 89 |
| 12 | Claude Sonnet 4.5Anthropic | 89 |
| 13 | o3 ProOpenAI | 88 |
| 14 | Grok 4.1 FastxAI | 87 |
| 15 | Gemini 3 Flash PreviewGoogle | 89 |
| 16 | Grok 4.20 BetaxAI | 86 |
| 17 | Grok 4xAI | 86 |
| 18 | o3OpenAI | 86 |
| 19 | GPT-5.1OpenAI | 85 |
| 20 | GPT-5.4 NanoOpenAI | 85 |
| 21 | GPT-5.3-CodexOpenAI | 85 |
| 22 | GPT-5.2-CodexOpenAI | 85 |
| 23 | GPT-5.1-Codex-MaxOpenAI | 85 |
| 24 | o4 Mini Deep ResearchOpenAI | 85 |
| 25 | o4 Mini HighOpenAI | 85 |
| 26 | Grok Code Fast 1xAI | 85 |
| 27 | o4 MiniOpenAI | 84 |
| 28 | Grok 4 FastxAI | 83 |
| 29 | Sonar Pro SearchPerplexity | 85 |
| 30 | Claude Haiku 4.5Anthropic | 83 |
Analyze molecular structures, predict drug-target interactions, and generate candidate compounds. Reasoning models evaluate pharmacokinetic properties and safety profiles.
Process trial data, generate statistical summaries, and identify adverse events. Large context handles full study protocols and regulatory submissions.
Search and synthesize scientific publications, patents, and clinical guidelines. Web search models access the latest research for up-to-date evidence summaries.
Draft IND applications, NDA sections, and compliance documents. JSON mode produces structured data for eCTD submissions and FDA databases.
Based on our composite scoring updated hourly, the top-ranked models are shown at the top of this page. Rankings consider benchmarks, pricing, capabilities, and community adoption.
Yes, several models listed on this page offer free tiers or are fully open-source. Look for models marked as Free in the pricing column above.
We use a composite scoring system combining benchmark performance, capability matching, pricing, context window size, and community adoption. Scores are updated hourly.
Rankings refresh every hour using real-time data from benchmarks, API testing, and community metrics. The data shown always reflects the most current performance.