Best Alternatives to Mixtral 8x22B Instruct (2026)
Looking for an alternative to Mixtral 8x22B Instruct by Mistral AI? Here are the top 10 alternatives ranked by our composite scoring system across benchmarks, community sentiment, pricing, and adoption data.
Score
by OpenAI
by OpenAI
by OpenAI
by OpenAI
by Google
by Google
by Google
by Anthropic
by OpenAI
by OpenAI
By our composite score, the top-ranked alternative is GPT-5.6 Luna Pro by OpenAI at 88 (+25 vs Mixtral 8x22B Instruct's 63). Of the 10 alternatives here, 10 score higher than Mixtral 8x22B Instruct, and GPT-5.6 Luna Pro offers a 1.1M context.
Among the priced alternatives, GPT-5.6 Luna Pro has the lowest output cost at $0.60 per million tokens (90% cheaper than Mixtral 8x22B Instruct).
GPT-5.6 Luna Pro has the largest context window among these alternatives at 1.1M tokens, suited to long documents and large codebases.
Why Consider Alternatives to Mixtral 8x22B Instruct?
Among the 10 closest llm alternatives to Mixtral 8x22B Instruct (composite score 63), 10 score higher, led by GPT-5.6 Luna Pro at 88. 8 cost less per token, and the lowest-priced is GPT-5.6 Luna Pro at $0.60 per million output tokens. Each card below breaks down how the alternative differs from Mixtral 8x22B Instruct on price, context window, and capabilities.
Our rankings evaluate each model across multiple signals updated hourly, so you can be confident these recommendations reflect the latest performance data. Browse the full LLM rankings or use our pricing comparison tool to find the best fit for your budget.